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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIN28
All Species:
18.18
Human Site:
S200
Identified Species:
33.33
UniProt:
Q9H9Z2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Z2
NP_078950.1
209
22743
S200
E
E
E
E
E
I
H
S
P
T
L
L
P
E
A
Chimpanzee
Pan troglodytes
XP_513232
209
22865
S200
E
E
E
E
E
I
H
S
P
T
L
L
P
E
A
Rhesus Macaque
Macaca mulatta
XP_001114640
143
15918
S134
E
E
E
E
E
I
H
S
P
A
L
L
P
E
A
Dog
Lupus familis
XP_854985
206
22464
H196
E
E
E
E
E
E
I
H
S
P
A
L
L
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3Y3
209
22701
S200
E
E
E
E
E
I
H
S
P
A
L
L
P
E
A
Rat
Rattus norvegicus
P62961
322
35711
Q265
N
E
E
D
K
E
N
Q
G
D
E
T
Q
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506004
274
29355
A210
E
P
Q
P
S
T
S
A
A
A
V
P
R
E
A
Chicken
Gallus gallus
Q45KJ5
202
22071
S194
E
K
E
D
M
H
S
S
A
L
L
P
E
T
R
Frog
Xenopus laevis
Q8JHC4
195
21688
E186
E
D
Q
P
I
T
E
E
Q
E
L
I
P
E
I
Zebra Danio
Brachydanio rerio
Q803L0
202
21867
S192
T
G
E
E
E
D
M
S
H
T
P
L
L
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRN5
195
21575
S182
S
K
S
I
S
N
N
S
S
S
S
A
A
Q
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P92186
227
25447
K207
A
A
R
M
A
A
E
K
S
S
P
T
T
S
D
Sea Urchin
Strong. purpuratus
XP_792032
234
25286
E212
S
P
K
T
T
A
E
E
A
S
P
S
S
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
65.5
95.2
N.A.
96.6
20.8
N.A.
53.2
80.8
62.6
66.9
N.A.
34.9
N.A.
26.4
33.7
Protein Similarity:
100
98.5
67.4
96.6
N.A.
98.5
34.4
N.A.
60.2
87
74.1
79.4
N.A.
47.8
N.A.
44
47
P-Site Identity:
100
100
93.3
40
N.A.
93.3
13.3
N.A.
20
26.6
26.6
40
N.A.
6.6
N.A.
0
6.6
P-Site Similarity:
100
100
93.3
40
N.A.
93.3
33.3
N.A.
40
40
46.6
40
N.A.
33.3
N.A.
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
16
0
8
24
24
8
8
8
0
47
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
16
0
8
0
0
0
8
0
0
0
0
8
% D
% Glu:
62
47
62
47
47
16
24
16
0
8
8
0
8
47
24
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
8
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
8
31
8
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
8
31
8
0
0
0
0
8
0
0
8
% I
% Lys:
0
16
8
0
8
0
0
8
0
0
0
0
0
8
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
8
47
47
16
0
0
% L
% Met:
0
0
0
8
8
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
8
16
0
0
0
0
0
0
0
0
% N
% Pro:
0
16
0
16
0
0
0
0
31
8
24
16
39
16
0
% P
% Gln:
0
0
16
0
0
0
0
8
8
0
0
0
8
8
8
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
8
% R
% Ser:
16
0
8
0
16
0
16
54
24
24
8
8
8
8
0
% S
% Thr:
8
0
0
8
8
16
0
0
0
24
0
16
8
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _